![]() Ko says cold sores look more like blisters than pimples and are often accompanied by flu-like symptoms or a tingling sensation before the sore appears. However, cold sores, also known as oral herpes, are caused by the herpes simplex virus and treated with antiviral medication. "Both lip pimples and cold sores can pop up on the border of the lips, and a lip pimple can be mistaken for a cold sore," says Ko. However, they tend to hurt more because the skin around your lips - with over one million nerve endings that sit close to the surface - is thinner and more sensitive than your other skin, says Ko. Like pimples you get elsewhere, these pimples are also caused by blockages or inflammation in your pores. It is not uncommon for people to get pimples in this area, says Christine Ko, MD, a dermatologist at Yale Medicine. If you've ever gotten a pimple at the edges of your lips, you know how painful it can be.
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